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Intraperitoneal administration of AFB 1 as a single dose of 2 mg or 17 g/kg increases markers of oxidative damage in the heart, such as thiobarbituric reactive substances, like MDA, and calcium (Ca) 2+ levels (124)

Exposure to iodine can also induce hypothyroidism in those with predisposing risk factors such as prior episodes of thyroiditis or Hashimoto thyroiditis