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Tobacco imports from Virginia and the Carolinas continued throughout the 17th and 18th centuries as the demand for tobacco increased, and the practice of smoking became widely accepted in Britain.

Tobacco use disorder ICD-9-CM: 305.1 Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent

The different patterns between IHD/stroke and lung cancer/COPD are affected by the different time-lag between smoking and peak smoking-related mortality 14, 23

Despite efforts to diversify Virginia's economy, by the end of the 1620s only one Virginia crop was drawing a fair market price in England: tobacco