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Extracts from tobacco rods were serially diluted and superfused over HEK293T cells expressing the human TRPM8 cold/menthol receptor activated by menthol, WS-3 and other synthetic cooling agents, measuring activity by Calcium-microfluorimetry as published (Supplementary file) 3

If you've been trying to quit cold turkey for months or even years but always relapse or even fall into long periods when you resume your regular smoking routine, then cold turkey may not be the best method for you

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