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Combined NNMT inhibitor treatment with reduced-calorie diet achieved 6.3 g cumulative weight loss versus 2.9 g with diet alone, and fat mass reduction was ten-fold greater with treatment (~29.3%) compared to diet switch alone (2.9%), while restoring fatty liver profiles to lean-control levels (Sampson et al., 2021)

But you may need supplements too, especially if you have one of the risk factors for deficiency and are diagnosed with low levels

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Whilst many GPs will not treat patients according to individual need (or feel their hands are tied), then it is essential to allow patients the ability to look after themselves