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Literature retrieval was performed primarily using Google Scholar and ISI Web of Knowledge due to their broad coverage of studies on chemical ecology, entomology, natural products, and agroecological pest management

While most reported toxicity cases have been associated with industrial accidents and manufacturing errors, it is important to at least be aware of the symptoms of selenium toxicity

This suggests that excessive GHK-Cu (or other copper peptides) might theoretically push skin MMP-1 concentrations beyond levels supporting healthy collagen production into ranges associated with collagen fragmentation and breakdown seen in older skin with naturally elevated MMP-1

The point that should be considered about non-selective TKIs is that the anti-tumor function of these inhibitors might be higher than that of selective c-Met inhibitors due to inhibition of multiple kinases