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[15] investigated the histopathologic features of OSF, observing mucosal changes such as atrophic changes, pigment incontinence, ulceration with granulation tissue, hyperplastic changes, dysplasia, and carcinoma at rates of 74.3%, 62.8%, 40%, 25.7%, 8.6%, and 0%, respectively

For tobacco use, the results were as expected: both FEV 1 and FVC steadily decreased with both current and lifetime exposure