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Our results showed that exposure to fullerenols at 10, 30 and 50 g/mL dramatically attenuated CYP3A4 mRNA and protein expression in HTR-8/SVneo cells, and the levels of ER mRNA and protein were also lowered in cells exposed to fullerenols at 50 g/mL

Collagen and matrix biology The first published paper documenting collagen synthesis stimulation by GHK-Cu appeared in 1988: fibroblast cultures increased collagen output when exposed to GHK-Cu at concentrations as low as 10 M, with peak activity around 1 nM (Maquart et al., FEBS Letters, 1988)

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Once again, it is difficult to determine when the problem arises: fetal life, prepubertal life, or during sexual maturity [47]