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The statistical methods used by commercial laboratories for reference interval generation are often not described and may differ between laboratories

There is ample evidence that bilirubin is a molecule with multiple biological functions, particularly antioxidant, signalling/hormonal and immunomodulatory effects

Sanabria-Cabrera J, Tabbai S, Niu H, Alvarez-Alvarez I, Licata A, Bjrnsson E et al (2022) N-acetylcysteine for the management of non-acetaminophen drug-induced liver injury in adults: a systematic review

Human studies using Lactobacillus as a probiotic have often demonstrated decreased body weight and/or body fat in a strain-dependent manner (for a review of human studies, see Crovesy et al., 2017 58 ), suggesting that the NNMTi-and-LD-mediated changes to Lactobacillus relative abundance may be critical to NNMTi-mediated weight loss