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Storage After Reconstitution Do This Store in refrigerator at 36-46F (2-8C) Keep away from light (store in box if possible) Use within 28-56 days of reconstitution Inspect for particles before each use Always swab the stopper before drawing Never Do This Never freeze reconstituted semaglutide Don't leave at room temperature for extended periods Don't use if solution is cloudy or has particles Don't use past the expiration date Never share vials or needles Stability note: Semaglutide is generally more stable than some other peptides

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The corresponding pharmacokinetic parameters are listed as follows: T max = 0.167 h, C max = 155 11.8 ng Eq./ml, AUC 0t = 4945 417 h ng Eq./ml, AUC 0 = 12956 2074 hng Eq./ml, average residence time (MRT 0-t ) of plasma total radioactivity = 33.2 1.03 h, and t 1/2 = 102 h (Table 9)