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Public and research interest in CBD has grown considerably due to CBDs potential health benefits

Closed pod systems (think the ones using nicotine salt cartridges) tend to deliver nicotine faster and at higher concentrations often 30-50mg which mimics the quick satisfaction of a cigarette 7

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Abbreviations: AM (alveolar macrophage), BAL (bronchoalveolar lavage), DC (dendritic cell), e-cig (e-cigarette), e-cig vaped extract (EVE), gen (generation), h (hour), min (minute), NK (natural killer), PG (propylene glycol), THC (tetrahydrocannabinol), VG (vegetable glycerin) Oral Mucosa The mouth is the first point of contact for e-cigarette aerosols entering the body