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Chemical research in toxicology, 2007, 20(9): 1309- 1314

Glycine: ~5g daily, an amino acid Sinclair believes helps regulate DNA methylation (the epigenetic labels that tell cells what type they are), potentially slowing the cellular identity loss that drives aging

Abstract In plants, exposure to temperature extremes, heavy metal-contaminated soils, drought, air pollutants, and pathogens results in the generation of reactive oxygen species (ROS) that alter the intracellular redox environment, which in turn influences signaling pathways and cell fate

Comparison to Other Procognitive Agents: In the same research groups studies, Dihexa was compared to other Angiotensin IV-derived compounds (Nle1-AngIV, Norleual)