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Commonly reported issues include mild gastrointestinal discomfort, particularly when starting the compound, and temporary headaches during the adjustment period

Disease-modifying treatments The success of the EAE model in recapitulating many autoimmune inflammatory aspects of relapsing MS spurred the development of many anti-inflammatory drugs

The cortical group exhibited significant associations between motor learning and RMT, EXC, SICI, and ICF in the ipsilesional M1, whereas diametrically opposing associations were observed in the subcortical group, with those with lesions affecting descending corticospinal pathway mediating this divergence

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