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Research has shown increased phosphorylation of extracellular signal-regulated kinases (ERK) 1 and 2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, which are molecules involved in cell growth, migration, and angiogenesis

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As the diffusion coefficient ( D ) characterizing the random motion (diffusion) of the particles is size-dependent, extended IDPs have smaller D compared to their compact, well-folded counterparts