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Nuclear Receptor Coactivator 4 ( NCOA4 ) functions as a selective autophagy adaptor that promotes ferritin autophagy degradation and induces cell ferroptosis 39

Electrophile Conjugation Glutathione S-transferases catalyse the addition of glutathione to numerous electrophilic molecules

The third pathway known as the indole route, involves the direct transformation of Trp into indole and its byproducts, such as indole acid formaldehyde (IAld), indole acetic acid (IAA), indole propionic acid (IPA), indole acetaldehyde (IAAld), and indole acrylic acid etc.[51]