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Description

Once p53 is freed, it moves out of the nucleus toward the mitochondria and sets off the intrinsic apoptosis pathway (a caspase-driven self-destruct program)

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doi:10.1016/j.fertnstert.2009.04.046

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He also hypothesized that senolytic drugs can selectively eliminate senescent cells from patients with SLE and rejuvenate these tissues, improve organ function, and promote disease dormancy

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The consistency of positive results across different systems is one of the compound's most compelling features

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