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fragilis can release a unique pro-inflammatory LPS-subtype and fragilysin, leading to an impaired intestinal paracellular and transcellular epithelial barrier, thereby allowing an already leaky barrier a gateway for the enhanced entry of microbiome-derived neuro- and entero-toxins into the circulation (Lukiw et al., 2021)

To date, there have been three animal studies and two human trials, none of which have shown any significant adverse reactions to the therapy

Why This Matters More Than the February Reclassification The February announcement moved peptides from Category 2 back to Category 1, which signaled intent

This review synthesizes clinical and preclinical findings to elucidate the relationship between gut microbiota dysbiosis and aberrant inflammatory signaling in the periphery and central nervous system in schizophrenia