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Pangenome analysis using Anvio illustrates the presence of the shared core SFB genome (Core, 925 gene clusters) as well as the proportion of gene clusters shared between two to four of the five phylogenetic groups (Cross-phylo, 647 gene clusters), and those within only one phylogenetic group (Phylo-specific, 1315 gene clusters) (Fig

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Later after 2002, Studies demonstrated that MetS and type 2 diabetes synergistically impact vascular thickness, leading to accelerated carotid intima-media thickness increase, a key marker of subclinical atherosclerosis (15, 16)