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The paper signalled a change in attitude towards researching these compounds, reflected by the fact that more than 460 psilocybin sessions have now been conducted at Johns Hopkins alone, ranging from investigating its use by cancer patients through to its effects on meditation

"It was a response to a public that was starting to worry about the health consequences of smoking." The ads hail from Stanford Research into the Impact of Tobacco Advertising, which Jackler founded in 2007 after his mother, a smoker, was diagnosed with lung cancer

The group also considered chemical structure, volatility and volume of use, among other factors

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