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Rare: headache, transient hyperglycemia

Zigouras, S., et al., Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats

Furthermore, there is an increase in memory B cells lacking the activation marker CD27 in peripheral blood of elderly individuals, a phenomenon also observed in chronic viral infections and autoimmune diseases such as systemic lupus erythematosus [359, 360]

Well, its shown strong potential in reducing the toxin-induced neural damage in those with Parkinsons disease in humans following positive results in animals