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TIGAR is induced in response to ROS [45] and protects cells from ROS-induced cell death [46]

10.1371/journal.pone.0162590 45 Lovric-BencicM.SikiricP.HanzevackiJ

Restless leg syndrome or periodic limb movement disorder require specific treatments (dopamine agonists, iron supplementation if deficient, other interventions), with Sermorelin providing minimal direct benefit for these movement disorders though improved overall sleep quality may reduce subjective impairment

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