ND heritability is enriched for genes expressed in cerebellum To assess whether heritability of ND is enriched in regions surrounding genes with the highest specific expression patterns in given tissue/cell type(s), we applied LDSC-SEG 44 using the EUR-specific ND GWAS meta-analysis results with reference to 205 tissues/cell types with publicly available gene expression data assembled from GTEx 45 (53 human tissues/cell types) and the underlying data that is used to comprise the Data-driven Expression Prioritized Integration for Complex Traits (DEPICT) tool 46,47 (152 tissues/cell types from humans and rodent models)
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"GLAAD protests 'South Park' f-bomb episode"
Harm reduction (reducing the risks of consumption) is, at best, an ancillary component of a comprehensive strategy for protecting the public health. With both tobacco and car use, the problem is economic at its core: the safest solution, usage reduction, is antithetical to the business aims of the industry, and thus a non-starter
