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Both serum potassium concentrations and the platelet count need to be monitored carefully after parenteral administration of cyanocobalamin

Recommended Dosage and Frequency After Bariatric Surgery The UK BNF standard regimen for confirmed B12 deficiency is 1 mg hydroxocobalamin IM on alternate days for two weeks, then 1 mg every three months

If pursuing intermittent fasting alongside the protocol, this period typically shows improved fasting tolerance

(Heffernan et al., Endocrinology, 2001) Early human trials: promising but modest Six Phase I/II human clinical trials were conducted, enrolling roughly 900 participants total