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Secondly, ferroptosis is a form of cell death that is associated with lots of signaling pathways, like hypoxia signaling (Zou et al., 2019), AMP-activated protein kinase signaling (Li et al., 2020), E-cadherin-NF2-Hippo-YAP pathway (Yang et al., 2019b), and NRF2-KEAP1 pathway ( Statements Author contributions JX and CM conceived and designed the work

Conclusions Unstable iron deposits within cells lead to an unbalanced redox state, causing a type of cell death known as ferroptosis which differs from other types of death

Neurological symptoms, such as numbness and tingling in the hands and feet, can also occur