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The percentage of adults who are current smokers declined steeply between 1965 and 1991, with an estimated 39 percent drop in the prevalence of cigarette smoking

Mensinga TT, Shouten JP, Rijken B, Weiss ST, Speizer FE, Lende van der R: The relationship of eosinophilia and positive skin test reactivity to respiratory symptom prevalence in a community-based population study

Users were instructed to "exhale the lungs of air, then after taking a mouthful of smoke, inhale the air into the lungs through the mouth allowing the smoke to go down with the air filling the lungs." Users were warned to "discontinue use if rapid pulse or blurring of vision appears." The label also warns that the inhalers are "not to be taken by elderly people except on competent advice." Although the product first appeared in the 1890s, ads promoting it as a treatment for asthma could be found into the 1950s

I change my cartridge after every third refill for the best flavor