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However, this rule only applies to e-cigarettes containing nicotine that are made or derived from tobacco, and therefore tobacco products containing synthetic nicotine fall outside of FDA jurisdiction, but on a case by case basis can be regulated by FDA as illustrated in FDA Commonly Asked Questions about the Center for Tobacco Products

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If needed, we will help your company resolve any agency actions brought forth by any federal, state, or local government agency

Treasury, which is tasked with monitoring and enforcing compliance for the expansive beverage alcoholic category