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Researchers at the University of Texas Medical Branch first characterized 5-amino-1mq in 2017 while searching for ways to inhibit NNMT, an enzyme they had identified as a key regulator of fat cell metabolism

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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

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