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Furthermore, as mentioned (Kang et al., 2018), a point combined, as mentioned, with counteracted pro-inflammatory and pro-cachectic cytokines such as IL-6, TNF-, cancer cachexiarelated pathways expression (i.e., FoxO3a, p-AKT, p-mTOR, and P-GSK-3) (Kang et al., 2018)

In the detection of pro-inflammatory factor secretion, we also found that OGD treatment promoted the expression of pro-inflammatory factors, indicating that the inflammatory response was enhanced (Figure 3H)