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We would therefore argue that genetic associations have shed light on the susceptibility of developing MS, but have not illuminated the fundamental cause of the disease

600 Interestingly, the Moco-sensing RNA motifs are present downstream of the operator-promoter regions of genes regulated by molybdate-bound ModE (Figure 21), including the high affinity molybdate transporter, modABCD

Tolerogenic peptide vaccines: the frontier The most advanced application of peptides in autoimmune disease is the development of tolerogenic vaccines