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Together, it can be concluded that intracellular selenium status (hydrogen selenide) regulates the expressions of seleno-GPxs primarily at the translation level by controlling the stability of their mRNAs as well as by facilitating the biosynthesis and subsequent incorporation of Sec into the peptide sequence (Fig

Data availability The data that support the findings of this study are openly available in TCGA database of PTCs utilizing the Firehouse web browser from the Broad Institute ( using TIMER2.0 ( a computational software for analyses of tumor immunologic, clinical, and genomic features 35

C.TapiaE.Molina-JijnE.et al (2017)