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Nutritional intervention is expected to become the third major treatment modality alongside physical therapy and drug therapy, bringing significant benefits to patients with mild to moderate OA and effectively reducing the proportion of severe OA patients, which allow more people to avoid the adverse effects of repeated drug treatment and the potential risks of surgery and prosthesis replacement

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The second step after filtering was performed with 0.23 M Pt GSTF8 and varying dilutions of the first step reaction in buffer to cover substrate concentrations from 389 M to 6.5 M