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It might be that the oxidative stress level was increased which further activated the advanced glycation end product (AGE) and receptor for advanced glycation end products (RAGE) in CS-induced endothelial cells and circulating CS directed toxicity on endothelial cells

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Overall, men can lose about 10 years of life expectancy and women about 11 years

The study was made up of 1,293 Montreal teens, with data collected every three months over a five-year period