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Cagrilintide versus tirzepatide Tirzepatide produces the highest weight loss of currently approved medications, with trials showing 21 to 25% reduction over extended treatment periods

Importantly, these compounds stimulate endogenous GH release, which mimics the bodys natural pulsatile secretion of growth hormone

Metabolic dysfunctionassociated steatohepatitis (MASH, formerly nonalcoholic steatohepatitis, NASH) is a major research focus, characterized by excessive hepatic fat accumulation, inflammation, and hepatocellular injury