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Malabsorption Issues : If you have conditions like pernicious anemia, Crohns disease, or have had weight loss surgery, vitamin B12 injections may be a more effective option due to the bodys difficulty absorbing B12 through the digestive tract

Clinicians should also avoid or adjust therapy in individuals with active peptic ulcer disease due to theoretical choline-mediated increases in gastric volume and in those receiving levodopa, as pantothenic-acid derivatives may interfere with levodopa absorption

In addition, B12 supplements may reduce the risk of developing dementia and Alzheimers disease, two conditions that are associated with cognitive decline