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(203) identified pyroptosis/ferroptosis as vulnerable pathways in pro-fibrotic proximal tubule clusters during maladaptive renal regeneration

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Docking of PLC to a separate site of TrkB leads to the production of diacylglycerol, a transient activator of protein kinase C (PKC) and inositol trisphosphate (IP3), and eventually mobilizes intracellular calcium (38)