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On the other hand, (ii) the first assessment of the analgesia in the absence of morphine (time "0"), the application of saline was administered 30 min in advance (time "-30 min"), the application of haloperidol or gastric pentadecapeptide BPC 157 or naloxone or saline 20 min in advance (time "-20 min"), and the application of saline 10 min in advance (time "-10 min")

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This overlap suggests that FOXO4s activation by oxidative stress and inflammation might follow similar mechanisms, pointing to a broader role of FOXO4 in stress and immune response contexts

If side effects develop, discontinue treatment and reevaluate with a clinician