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In addition to the protein folding, enzymatic reactions within endoplasmic reticulum can also produce ROS

Administration of lipoic acid (200 to 1,800 mg/day for 2 weeks to 1 year), alone or together with other nutrients, was found to lower fasting blood glucose and insulin concentrations, insulin resistance, and blood HbA1c concentration a marker of glycemic control over the past few months (60)

The clear explanation and actionable dietary tips, especially about reducing saturated fats and increasing antioxidant intake, have helped me manage symptoms better

It is expected to be safe enough but there is an issue with cancer patients