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Around 25% of patients experience gastrointestinal side effects and about 5% are unable to tolerate metformin (163)

In: Das PK, Sejian V, Mukherjee J, Banerjee D

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This is key since bisphenol-A molecules are joined by ester bonds, which are disrupted by high temperatures or pH chances, and subsequently released on water and food (Wagner and Oehlmann, 2009), thus tempting to speculate on the consequences of chronic exposure to these molecules, especially in post-menopausal women