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Before all downstream analyses, duplicate reads were removed using the MarkDuplicates command in picard-tools version 2.26.11 ( From the ChIP-seq, CPM values in the genome tracks were calculated by subtracting those in the input tracks as the background value for each cell

The colonic lining primarily absorbs water and electrolytes, and introducing coffee repeatedly can disrupt the delicate balance of the intestinal microbiome and damage protective mucosal barriers

Key Takeaways Glutathione is an essential molecule since it has an important role in detoxification processes and immune function

The RARA::RXRA and RARA::RXRG complexes are heterodimeric protein complexes formed by the retinoic acid receptor alpha (RARA) in conjunction with either retinoid X receptor alpha (RXRA) or retinoid X receptor gamma (RXRG) 59