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The extinction coefficient 43.6 M 1 cm 1 of H 2 O 2 at 240 nm was considered for calculations

These observations are very important as lactate does not only act as an osmolyte but is also an essential energy metabolite, reflecting potential cerebral energy impairment in patients with HE

The MOTS-c 5-amino-1MQ stack protocol represents one of the most investigated combinations in cellular energy regulationpairing a mitochondrial-derived peptide with a nicotinamide N-methyltransferase (NNMT) inhibitor to target fat oxidation through two complementary pathways

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