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Those who undergo GI surgery, like removal of intestines or gastric bypass, may also have difficulty with B12 absorption (4, 5)

Parenteral administration of vitamin B12 effectively and promptly replenishes B12 stores

Avoid Alcohol: Refrain from alcohol consumption for at least 24 hours before your treatment, as it can interfere with nutrient absorption

Reviewing previous IBD treatment response: If a biologic or advanced IBD treatment has not worked as expected, it may be appropriate to review treatment history, disease activity, drug levels, antibodies, timing of response and whether symptoms are due to inflammation or an overlapping condition