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Nat Rev Cancer 8:96775 Orrenius S, Gogvadze V, Zhivotovsky B (2007) Mitochondrial oxidative stress: implications for cell death

Positive RF (1:300) : Rheumatoid factor (RF) is an autoantibody found in approximately 75 to 80% of RA patients (England et al., 2025)

Development of kidney disease is associated with the enzyme myeloperoxidase (MPO), abundant in neutrophils catalyzing the transformation of hydrogen peroxide (H 2 O 2 ) to hypochlorous acid (HOCl), a powerful oxidizing cytotoxic agent, according to the reaction HOCl has been found to be responsible for renal dysfunction among obese children

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