In the case of pronounced absorption disorders, for example as a result of gastritis or after removal of the small intestine, in Crohn's disease, diverticulosis and the so-called blind-loop syndrome, there is a gradual decrease in the vitamin B12 store in the liver, which can turn into a manifest vitamin B12 deficiency
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Changes in electrical activity of the heart along with an increase in sympathetic tone, catecholamines (epinephrine or adrenaline, norepinephrine or noradrenaline) and cortisol can contribute to the development of heart palpitations
Morphologic features of mucosal injury were based on different grades of epithelial lifting, villi denudation, and necrosis