Ingredients: Water, Dipropylene Glycol, Glycerin, Niacinamide, Octyldodecanol, Helianthus Annuus (Sunflower) Seed Oil, Butylene Glycol, Trehalose, Pentylene Glycol, 1,2-Hexanediol, Eriobotrya Japonica Leaf Extract, Coptis Japonica Root Extract, Mentha Viridis (Spearmint) Extract, Sodium Hyaluronate, Theobroma Cacao (Cocoa) Extract, Centella Asiatica Leaf Extract, Argania Spinosa Kernel Oil, Sesamum Indicum (Sesame) Seed Oil, Chitosan, Serenoa Serrulata Fruit Extract, Caprylyl Methicone, Panthenol, Polymethylsilsesquioxane, Propanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Olivate, Polyglyceryl-10 Behenate/Eicosadioate, Ammonium Acryloyldimethyltaurate/VP Copolymer, Sorbitan Olivate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Ethylhexylglycerin, Sorbitan Isostearate, Adenosine, Palmitic Acid, Hydrogenated Lecithin, Glutathione, Phosphatidylcholine, Polyglyceryl-10 Laurate, Dilauryl Thiodipropionate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Sodium Phytate, Allantoin, Madecassoside, Lecithin, Cellulose, Sodium Phosphate, Polyglutamic Acid, Dextrin, Asiaticoside, Cysteine, Tocopherol, 3-O-Ethyl Ascorbic Acid, Arbutin, Bisabolol, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-10, sh-Polypeptide-11, sh-Polypeptide-3, sh-Polypeptide-59, sh-Polypeptide-9, Cholesterol, Ascorbic Acid, Beta-Sitosterol, Ascorbyl Glucoside, Ceramide NP, Xanthan Gum, C12-16 Alcohol
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H4R plays a key protective antibacterial role in innate immune signaling As both adaptive T-cell and innate immune responses likely contribute to inflammation in colitis, we wondered what the effect of losing both adaptive immunity and this novel innate immune H4R-mediated pathway would be on mice undergoing experimental colitis
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