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Upon activation, free radicals such as nitric oxide (NO) and superoxide are released, which elevates oxidative stress contributing to pathogen elimination and local tissue damage ( Migraine Pathogenesis: Role of Oxidative Stress, Neuroinflammation, and Mitochondrial Dysfunction Migraine is defined as a neurovascular disorder involving cortical spreading depression (CSD), neurogenic inflammation, and dysfunction in cranial vascular contractility ( Oxidative Stress Oxidative stress role in migraine pathogenesis is emphasized by multiple studies
Neuropharmacology 51:789804 Brennan GP, Garcia-Curran MM, Patterson KP, Luo R, Baram TZ (2021) Multiple disruptions of glial-neuronal networks in epileptogenesis that follows prolonged febrile seizures
By helping us understand what people need and making us appreciate nature more, psychedelics may inspire products and systems that are innovative, beautiful, profitable, and also good for the planet
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